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What are common causes for false-positive CA-125 Serum levels?
What are common causes for false-positive CA-125 Serum levels?
The CA-125 blood test, sometimes used as an ovarian cancer screening, has a high false-positive rate. Some possible conditions associated with an false-positive are fibroids, endometriosis, pancreatitis, liver disease, inflammatory bowel disease, and benign ovarian cysts. I am looking for a COMPLETE list of ALL possible conditions associated with false-positive results. I’ve done a Yahoo and Google search but am not satisfied with the results. I seem to remember that rheumatoid arthritis is also associated also….for instance.
If you are able, please provide a complete list. Thank you
Denisedds….
Yes, I realize it is a long list… but that is exactly what I am looking for.
The CA-125 is not intended to be a screening test and should never be sued as one. There may be a complete list of what may cause a false positive somewhere, but there is little need for such a list in a medical setting, as clinicians do not rely on lists. Any irritation in the abdomen can cause a positive result. It’s especially inaccurate in premenopausal women (accuracy rate of about 50%); endometriosis, early-stage pregnancy or even normal hormonal fluctuations can lead to elevated CA-125 levels. Therefore a complete list can be very long.
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